CATalyst Antioxidant Enzyme Formula – 2 oz

(109 customer reviews)


An all-in-one, Grade-A supplement that helps support your cat’s joint function, immune system, digestive health, kidney health, skin & coat as well as free radical reduction. Our powerful Liquid Antioxidant Formula helps optimize the whole health of your fine feline very quickly!


Key Ingredients: Lipase, Amylase, Catalase, Protease & Superoxide Dismutase

1-4 month supply – depending on cat weight & bottle size purchased.

Purrfect for:

  • Joint Support
  • Arthritis
  • Immunity Support
  • Digestive Health
  • Shedding / Skin & Coat
  • Hairballs
  • Pancreatitis
  • Diabetes
  • Hyperthyroidism 
  • Feline Hyperesthesia Syndrome
  • Inflammation
  • And Much More!


In stock (can be backordered)

This all natural supplement is truly the Cat's Meow. The CATalyst Antioxidant Formula is the every day, enzyme and antioxidant rich supplement that provides the live nutrition needed to optimize the health and wellness of our feline friends. Our cutting edge ingredients come in a powerful liquid formula - easy to add to your cat's food! CATalyst features an absorbent form of Superoxide Dismutase (SOD), made from natural plant extracts. SOD is the body's powerful defense against free radicals and the inflammatory reactions they cause. CATalyst supports healthy joint function, immune function, digestive health and skin/coat - all in this easy to use formula.

How it Works:

If your cat weighs 1-10 lbs., simply add 1/4 teaspoon to your cat's wet food, once daily. One 2oz bottle will last one cat about 2 months. (4 months with 4oz bottle)

If your cat weighs more than 10 lbs., simply add 1/2 teaspoon to your cat's wet food, once daily. One 2oz bottle will last one cat about 1 month. (2 months with 4oz bottle)

This dosage may be safely doubled to see faster results.

CATalyst is plant, animal and human friendly.


Active Ingredients: Amylase- 9.01USP, Catalase-13,217 USP, Lipase-11.0 USP, Protease-5.00 USP, Superoxide Dismutase- 12,508 USP

Inactive Ingredients: Protein- 1.85mg, Sodium- 0.42 mg, Fat – 0.24 mg, Carbohydrates- 3.45 mg.

Have Questions? Email us at or text us at 702-466-1150

Additional information

Weight 2.2 oz
Dimensions 2 × 2 × 6 in

2 ounces, 4 ounces

109 reviews for CATalyst Antioxidant Enzyme Formula – 2 oz

Based on 96 reviews
Showing 75 of 96 reviews (5 star). See all 96 reviews
  1. Connie

    I can’t believe the difference this has made in my cat’s energy! Instead of sleeping all day, now he spends a lot of time playing and running around. Thank you, it is easy to use and he loves it in his canned food!

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  2. Norma A.

    My cat Buffy is 5 years old and was walking really slow like she was hurting. I gave her the catalyst and she seems to be doing better now thank you.

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  3. Michele L

    Very happy with this product! I have an 18 year old cat that has started trouncing through the house like a kitten again. I’ve spent a lot of time looking for a great all-natural product to help my cat with his arthritis and this is by far the best product around… and at a good price! I’ve already placed another oder for more and will recommend this to others.

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  4. Marcie

    I order this every month for my cat. It has helped her joints so much at her age and I feel like I’m going to have her around longer now.

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  5. Marsha F.

    Been using this for 14 yr old tabby and he has more energy and goes up the stairs now. Thank u.

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  6. Robyn (Verified Customer)

    My cat Pepper was diagnosed with TMJ over a year ago and was not given more than a few months to live. The arthritic pain in the mouth joint caused so much discomfort that eating became difficult. I have tried numerous products and have been very encouraged by the results of CATalyst. Pepper does not exhibit pain and is eating more frequently. My next order of the product will incorporate the Vitamin C formula to see if there is more improvement. I would highly recommend this product for any cat that is suffering from arthritis or mobility issues. It is simple to use and fast acting.

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  7. Amber

    This product I believe saved my cat Coffy’s life. He is approximately 18 years old and was diagnosed with Hyperthyroidism, He was throwing up a lot and had the runs all the time, and was always hungry. This has been a complete turnaround since I started him on this one a day I put it in his wet food and he has more energy, no more throwing up or runs, and gained weight! I am more than thrilled that we found these ladies at the Cat Con and they suggested it. I truly believe this is a miracle worker for my cat 🙂

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  8. Julie Lapitino (Verified Customer)

    My cat, Rootie, is 16 years old. She’s had some kidney problems ,allergies, and problems with arthritis. I started giving her the catalyst 3 months ago and I have noticed a positive difference in her energy, movement and overall well being. Thank you for a great product.

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  9. Paula Filius (Verified Customer)

    Took in some strays so wanted to give them and my own cat anything that would help with their overall health. Jae helped me choose this and Oxy-Cat and I’ve been very happy with both. Love their products and the Two Crazy Cat Ladies.

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  10. Deb

    Our cat’s skin and coat are healing beautifully! Due to Feline hyperethesia she was basically attacking her back end and making it raw and angry. Within one week , the episodes have almost disappeared and she is a much happier kitty. We also changed her food to raw food kibble and canned salmon. Thanks so much and I will continue using Catalyst on a daily basis!

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  11. Dayna L Neufeld (Verified Customer)

    I have only been using the CATalyst for the last month but it has worked wonderfully…My cat used to throw up 2-3 times a week, but he has literally not thrown up once since we started with this product. As a senior, I have also noticed he is much friskier and playful than he was before we started on it. I love it and will continue to purchase..thank you ladies!

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  12. Poison Ash (Verified Customer)

    Best thing I have ever given to my cats. One of my cats had a liver failure, and my mom actually gave me the bottle to give to him cuz his other medications were not working very well. After a week of him taking this. His skin went back to a normal color, he was playing around again, gained some weight, and almost completely back to his old self!! I got another bottle as soon as I saw how amazing it is!! Thank you for saving my baby Ninja!!! 🖤

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  13. Sue C. (Verified Customer)

    My Sammie has Twitchy Back. I tried this stuff because it was natural (he has heart issues and I wanted something non pharma). His episodes have drastically decreased and his fur has gotten amazingly softer. I highly recommend this product. Sammie will not eat wet food. I mixed it with the dry and he and the other cat just gobble it up.

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  14. srhine421 (Verified Customer)

    This product is beyond amazing!! I have a part Maine Coon cat with long hair and before using this product, he would throw up his food several times a month and eventually a hairball. Since I started using this, the only time he throws up now is when he’s got a hairball. I wasn’t sure how much this was helping until I ran out of CATalyst and he went maybe a week or two without it and started throwing up the food again. I am a true believer in it!! He will never go without it again! THANK YOU SO MUCH CRAZY CAT LADIES!! :o)

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  15. Joanne Halpin

    I just got a blood panel report from my vet. My cat will be 18 years old in a few months and there were no thyroid issues. No kidney issues. No conditions of any kind that would require medication or follow-up care. I left a review under the OxyCat product, but I use this and the OxyCat every day. Two Crazy Cat Ladies get all the credit for keeping my senior cat healthy and well!

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  16. Joanne Halpin

    My cat will be 18 years old in a few months and a recent trip to the vet showed no thyroid kidney issues…no conditions of any kind that would require medication or follow-up care. I left a review under the OxyCat product, but I use this and the OxyCat every day. Two Crazy Cat Ladies get all the credit for keeping my senior cat healthy and well!

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  17. Stephanie McCurry (Verified Customer)

    I originally ordered this for my Kitty Sunshine because she was a senior lady and had stopped eating. Shortly after, she became my angel💔I started my new kitten, Hunter Ray, on this and we just finished the bottle. We’ve been out for about 1 1/2 weeks and he’s started shedding more and sneezing. Getting ready to order another bottle. This works wonders for him! Thank you💗

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  18. butterfly_96319 (Verified Customer)

    I am on my 2nd bottle of CATalyst. Before I found this my cat was very sensitive to touch on his back towards his tail. Once I started using this I was able to pet him again without him becoming agitated. Glad the cat ladies are around to help rescue the cats.

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  19. Ora Lee Peters (Verified Customer)

    Great product. Since I have been adding CATalyst to my 3 cats food, they are having less hairballs and don’t throw up their food like they use to.

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  20. Freda (Verified Customer)

    I have 2 cats, my girl has always had trouble with UTI for years, on and off antibiotics. Always urinating small amts, frequently, sometimes with blood in it. Got tired of placing her on antibiotics a few times a year. I did research. Learned it is not Infection (UTI) but Inflammation. Idiopathic, so no one knows quite sure where it comes from. What I did learn, food (kibble–is really bad for cats, raw is best but at the very least canned), stress is a factor (and since I got my boy, they are at each other, as well as my 2 dogs who want to play with her, but she’s not having it). Got them off kibble , and on raw food (no easy feat! and made sure I added a good supplement with taurine), got some holistic formula for urinary tract health. Helped a little but not any great big deal. Came across this site while searching. I first tried the Cat Calm (for both) and urinary Catplus (for my girl) and it made a significant difference. I recently added CATalyst (I read it helps with the inflammation), and that did the trick. I highly recommend these 3 products to anyone who has problems with their cat’s urinary tract. Also, my boy had a blockage about 2 1/2 yrs ago. Hospitalized and placed on Science Diet urinary formula (worst crap in the world, BTW). Stopped that and placed him on canned and transitioned to raw. He takes the Catalyst and cat calm. I have never had an issue with him. I also add a little extra bone broth to their food or water.

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  21. Ceran Tait (Verified Customer)

    I love the product, helps öy cat a lot!

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  22. Sally (Verified Customer)

    I got this for my senior kitty with pancreatitis. Ever since I started adding it to his wet food, he eats it right up with no hesitation. He’s been taking the CATalyst supplements very for a couple weeks and they seem to be improving his appetite and vigor. He also takes prednisolone every other day.

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  23. Lauren Walsh (Verified Customer)

    I got this for my 2 kitties because they were shedding constantly! They’ve only been on it for a week or so and I already see a reduction in the shedding. Great product !!!

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  24. Denise (Verified Customer)

    My 5 year old male kitty has an autoimmune disorder. He has facial breakouts. I’ve been giving him Catalyst for over a year. The breakouts have become way less frequent and they don’t amount to much and go away quickly. He’s a very strong and healthy cat. I put it on his wet food once a day and he loves it.

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  25. Victoria (Verified Customer)

    My cat is 18.5 yrs old. She is beginning to lose body volume, you know the boney look. She is Russian Blue so her fur is very thick and of course she cannot groom properly. Usually twice a year she gets dandruff on her back towards rear. And the skin must get sore because she does not like me to really even brush it. I began the CATalyst a couple weeks ago and her skin looks much better. I’m sure it is helping her insides also but she is getting old and moody. I pamper her beyond normal because she has been my only companion basically since she was born. She is a ‘daughter’ to me and I treat her as a human. I give her good products like this one. I also use the natural Flea spray. Its comforting knowing it’s natural and I do not have to worry about spraying it on her bedding and the furniture also. Thank you ladies for your CAT LOVE and sharing.

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  26. Madison Moreno (Verified Customer)

    When I first bought Catalyst I was originally getting it to help three of my kitties who have very sensitive tummies. I decided to start giving it to all of my kitties and can’t believe how my cats have CHANGED for the BETTER!
    Their coats are stunning! Not only are they soft and shiny, but they’re not shedding as much and dander is less.
    My arthritis kitty seems to feel much better in her hindquarters and isn’t limping as much. I can tell she feels better.
    And the reason why I bought it in the first place, the tummies? They are doing great! I’m not seeing as many furballs around the house, which is fantastic when you have 7 cats! Plus the sensitive tummy kitties are doing better with foods. Thank you Two Crazy Cat Ladies!

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  27. Shannon C (Verified Customer)

    My cat resists every effort to give her oral medication. She’s cleverly figured out how to lick the cream cheese off pills and spit them out. This I just pour in a saucer and she laps it up. Dry skin is much better.

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  28. Theresa Bourdage (Verified Customer)

    My Cat was throwing up a tiny amount of her food at least 3 times a week. This has not happened in the last 2 weeks since starting her on Catalyst.

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  29. stamps4fungin (Verified Customer)

    I’m assuming that my cat is throwing up hair ball less, is due to this Catalyst product. He is only 6, so I don’t think his energy is any different. Thanks.

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  30. Linda Rose Stahl (Verified Customer)

    I am so very grateful 🙏 I found the two crazy cat 🐈 😻 ladies, and their preparations for kitties.My Chloe is one very lucky girl!

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  31. Linda Rose Stahl (Verified Customer)

    I am so very grateful 🙏 I found the two crazy cat 🐈 😻 ladies, and their preparations for kitties.My Chloe is one very lucky girl! So is my silly Callie, for that matter and I am a lucky 🐈 😻 mom

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  32. Pam Webster (Verified Customer)

    We’re not exactly sure how old Mowgi is, but we’re thinking he might be 12. He has arthritis, but when he’s on Catalyst, he’s able to run around and play with the younger cats with no problems. Thanks!

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  33. anniliesewood13 (Verified Customer)

    Catalyst is a miracle product. After my cat was diagnosed with chronic pancreatits she wouldn’t eat by herself and had nauseas. Now she is eating by herself and more lively. THank you, Cat Ladies.

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  34. Dina (Verified Customer)

    My 12 yr old cats are picky, so I’ve started with 1 drop in their wet food, twice a day. One of them had been waking me up at 4am every morning with the hairball vomit gag song which is why I tried this product (found these gals on tiktok). I’m about 2 weeks in and he has only done the vomit gag once. I feel like both of them seem just happier, if that’s possible. They are pretty spoiled. Will continue to use this product and increase up to he recommended amount as I can.

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  35. Nicolette (Verified Customer)

    I just received this product a few days ago and I’m already in shock with what a difference it has made for my oldest cat. We feed her wet food 4x a day, but the first meal of the day has to be a really small portion because she’ll throw it up, I figured that’s from not eating all night. Every time I looked that up, of course I was told by Google to run to the vet because there could be a serious issue. But I know my cat, we take her to the vet regularly and she’s healthy! She just throws up if she eats too much for her first meal. I saw this product on tik tok and I ordered it right away. After just a few days, we can now feed her larger portions in the morning and she doesn’t throw up, and she has so much more energy! She used to spend the whole day sleeping, and now she’s chasing balls! When I saw her chasing that ball I was in shock. She’s currently right next to me grooming herself when usually she’d be in bed sleeping. I am so grateful for this product, I could cry. Thank you cat ladies!

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  36. Marjorie Gross (Verified Customer)

    I’ve only had the product for a week, but really trust the Cat Ladies, so am anxious to see the results of using this for a while. I have 4 cats so one bottle isn’t enough. About to order more.

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  37. Shumail laeeq (Verified Customer)

    Best , my cat is doing much better now .

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  38. Anonymous

    My cat seems to be doing a lot better after using this Catalyst.

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  39. Carla G (Verified Customer)

    Miss Maggie has only been on this for one week but I noticed she has not coughed up any hair balls which is a big improv . She is 14 yrs old and seems to getting a bit more playful. Look forward to seeing what else improves after a month!

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  40. Pam Roussell (Verified Customer)

    Catalyst is something I add to my cats’ food regularly to provide digestive and antioxidant support. It has so many benefits there’s no reason why not to use it! Plus the fact that it’s liquid makes it easy to mix into wet/raw food. I recommend this all the time to clients!

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  41. Courtney (Verified Customer)

    Our kitty was diagnosed with early pancreatitis, and kidney disease. She started to throw up a lot and wasn’t getting up unless to eat and use her box… I remembered that enzymes can help w/ digestion, so I did a search online and found “Two Crazy Cat Ladies!” This formula in a matter of days brought life back to our sweet little girl. It’s a miracle! My vet only offered Prilosec and anti-nausea meds… I was worried she wasn’t going to make it! Now, she doesn’t seem to be in pain, she’s totally finicky, but doesn’t mind the taste, and even her coat has more luster! Thank you Two Crazy Cat Ladies! I’m telling my vet about this!! Every cat owner should use it. Wish I knew sooner. I hope to have more time left with or lovey pet:) ❤️

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  42. Barbara burley (Verified Customer)

    This product is amazing my cat has scabs from constant scratching his skin ripples when touched on his back and he cant stand being touched along his spine to his rear he does have a allergy to flea bites and i have done everything possible to help him there are no fleas and he still chews himself all the time i decided to try this item as i have heard good things and it has been 1 week and i can already see a huge difference hes more calm scratching less his scabs are getting smaller its only been a week i have high hopes that this is going to give him some relief and a better quality of life

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  43. Ruth (Verified Customer)

    My sweet 17 year old boy was diagnosed with end stage renal failure. I had been thru this years before with another kitty and researched to see if there was anything i could do to help him. Along came catalyst. It has been a year. He is thriving! Great appetite, gaining appropriate weight, allost no vomiting, and is happy! Best news is there is no sign of kidney disease in his bloodwork! His thyroid is now a bit wonky but we are working on that. So grateful for catalyst!

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  44. Cindy (Verified Customer)

    Used this product for a few years. Really like it.

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  45. Melanie (Verified Customer)

    I’m over the moon about CATalyst EF! 2 19 yr old retired barn cats were showing all the signs of arthritis. A week on CAF made a difference; a month later they’re at least 4 years younger. Easy to add to food and a little goes a long way.

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  46. Lisa (Verified Customer)

    So far, so good with this enzyme formula (it’s only been a week!) My cat was vomitting every morning and the only solution I’d found was giving her a tiny bit of food, wait an hour then give her more. It was stressing us both out. She is very finicky so I was worried she’d smell or taste this and walk away. We’ve been using it a week and so far, no vomitting and no finicky cat issues. I’m hopeful this is the solution we were searching for!

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  47. Andrea (Verified Customer)

    My 15 year old cat was diagnosed with hyperthyroidism last year & really struggled with weight loss, hair mats, lack of energy, etc. The vet ran several tests which all came back normal and literally thought she was going to die with how she was presenting. I started following the two crazy at ladies & learned about this product so I though why not since the reviews looked good. I have only been using it for about a week & no more mats & if she does have one it’s really small & she’s eating so much better. Her energy is up & she seems more like her old self! I have been telling all of my friends about this product because it’s truly amazing!!! Highly recommend!!

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  48. Carol Dufner (Verified Customer)

    I was a sceptic as so many people make claims. It seems to be working! He hasn’t thrown up in a week. Hopefully he continues on this protectory. He is our 181/2 year old love bug. Want him to stick around.

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  49. Kim Irwin (Verified Customer)

    AMAZING!!!! My 5 year cat has been dealing with some type of allergy (not food related) for over a year now where he was scratching at his face causing sores/scabs on his cheeks and in the area between his eyes/ears. After being on Apoquel (an allergy medication for dogs), his scratching decreased greatly. He’d still have some itching here and there but not like it was before. After being on CATalyst for 4 weeks, he has completely stopped scratching. I’ve also stopped giving him his daily Apoquel pill – CATalyst is that good!!!

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  50. Anonymous (Verified Customer)

    Skin and coat are so much shinier now!

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  51. Ray Y. (Verified Customer)

    Works well for my cat. Very prompt delivery.

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  52. Ana (Verified Customer)

    My one year old cat has sensitive stomach and this product has helped her more than any other medication without the unpleasant struggle of giving her the medicine. She loves Catalysis and so do I.

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  53. Mary B. (Verified Customer)

    Very satisfied with this product. My cat has IBS , so has digestive issues. After finding a great food for her and adding catalyst to every meal, her tummy issues are under control. Thank you for such a great product. Mary and Yuki😻😻😻

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  54. Laura O. (Verified Customer)

    My cat eats food he would not previously eat when i put this on top!

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  55. Jae

    Love this

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  56. Tami T. (Verified Customer)

    Just started using so need a little time to see if it’s working!

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  57. Kathryn C. (Verified Customer)

    Both very finicky cats are drinking this in their water. I’m looking forward to seeing the improvement! Customer service responded to a shipping issue (it was USPS fault, not theirs) swiftly and rushed a replacement to me! Great customer service and they care about cats so I appreciate that.

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  58. Deborah (Verified Customer)

    Received much quicker than from Jackson Galaxy.

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  59. Debbie (Verified Customer)

    Had made a huge difference in my 15 year old in just a short time, eliminated the vomiting and she’s eating better too. So thankful.

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  60. Nancy Allen (Verified Customer)

    This product has helped relieve my cat’s skin sensitivity.

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  61. Charles (Verified Customer)

    Real fast delivery. Been using this stuff and it’s really calmed down my cat. Time for a refill

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  62. Michelle (Verified Customer)

    I have been using oxy-cat and catalyst for 2 weeks now. My senior girl was recently diagnosed with asthma and I wanted to improve her overall health, as well as treat her asthma. She has suffered from dry, itchy skin (dandruff) chin acne, hairballs, yeast in ears, arthritis and general inflammation. I had high hopes for this product and it has not disappointed! Her chin acne is gone. Her skin is less flaky and her coat is soft and fluffy. She is having better bowel movements and grooming more. She is more active and is less bothered when I touch her arthritic spot on her back. I’m hoping it will also help with her teeth but she won’t let me look at them lol. She is getting Catalyst once a day and oxy-cat twice a day in her wet food. She has no problem eating it up. I have zero regrets and will be buying more. Shipping to Canada was quick. Took exactly one week to arrive.

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  63. Teresa W. (Verified Customer)

    Great product!

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  64. Charles (Verified Customer)

    Real fast delivery will definitely do business again

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  65. Melissa L. (Verified Customer)

    My cat had an allergic reaction to food and her lip swelled. We eliminated that food but the swelling never went completely away. She then got really sick and ultrasound showed she had inflammation surrounding some of her organs. I found these supplements and it’s been life changing for my girl. I didn’t know what to expect but I was desperate to help her so she didn’t have an episode again. After a few weeks of using Catalyst, my husband and I noticed her lip was normal size again. It hadn’t been normal for over a year. If this supplement got rid of the inflammation in her lip, it makes me believe it got rid of the inflammation throughout her body. She’s happy and full of energy now

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  66. Belinda J. (Verified Customer)

    My senior cat thrives on this! Her coat was perpetually “greasy” even after she groomed herself and she had runny eyes sometimes. After a few months on this, her coat is now SUPER soft and shiny and her eyes cleared up and have stayed healthy. She also is just noticeably more healthy and peaceful in general 🙂

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  67. Kenneth Furger (Verified Customer)

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  68. Elizabeth

    My cat is 11 and started having a lot of sensitivity to her back, especially towards her tail. I would brush her to get the dandruff and try to give her some relief but she acted like it was painful. I would find her rolling around on her back to itch her skin and also would bite at her paws aggressively. I purchased this product a few weeks ago and have been adding it to a little bit of wet food each day. It is amazing how much this has helped! The dandruff is gone, I can pet her back without her reacting, and her attitude has changed! She is so loving and wants to be pet constantly now. I am ready to invest in my second bottle! I can tell she feels so much better and is thankful for the help!

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  69. Denise Keefe (Verified Customer)

    This is a great product! It has really helped my kitty with his autoimmune problem!

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  70. Keiflyn Dunning (Verified Customer)

    Medicine truly works my cats 18 and thriving Aloha

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  71. Anonymous (Verified Customer)

    Our cat hasn’t vomited since we started using this in her food. She has IBD/ small cell lymphoma.We see this is helping with her. She used to vomit inconsistently. We also ran Ucari food and environmental sensitivity test and found out many foods that we were feeding tuned out to be something that she is severely sensitive to. We stopped giving those and she vomited less and less but we will monitor.

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  72. Anonymous (Verified Customer)

    My 10-year-old cat has arthritis. He gets a monthly injection of Solensia (which reduces the symptoms of osteoarthritis) and uses this supplement. Since using both projects, he acts like a much younger cat. He runs up and down the stairs, he wrestles his 2-year-old brother, and likes going on walks a few times a week. Additionally, he likes the taste of the supplement and doesn’t mind having it administered on his wet food.

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  73. Donna R. (Verified Customer)

    Price was about the same as Amazon products and I’d rather give to small business entity

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  74. Cassandra (Verified Customer)

    Great product to keep my cat healthy!

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  75. Sheri Gravenmier (Verified Customer)

    Absolutely incredible service and the product worked amazingly in just a few days!!!

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